Research Comparison
CJC-1295 (without DAC) vs Tesamorelin
A side-by-side research comparison of CJC-1295 (without DAC) and Tesamorelin drawn from Cedar Peptides' peptide database records.
CJC-1295 (without DAC)
CJC-1295 (without DAC), also known as Modified GRF 1-29 (Mod GRF 1-29), is a short-acting synthetic analog of growth hormone releasing hormone (GHRH). It is designed to stimulate endogenous growth hormone (GH) release in a pulsatile, physiologically consistent manner. Unlike the DAC-modified version, this variant has a very short half-life, allowing precise control over GH pulses and reducing the risk of receptor desensitization. It is primarily used in research focused on recovery, anti-aging, body composition, and endocrine function optimization.
Tesamorelin
Tesamorelin is an FDA-approved synthetic growth hormone-releasing hormone (GHRH) analog designed for treating HIV-associated lipodystrophy. This 44-amino acid peptide with a trans-3-hexenoic acid modification at the N-terminus selectively reduces visceral adipose tissue while preserving subcutaneous fat, making it unique among growth hormone therapies. Approved under the brand name Egrifta, tesamorelin stimulates pulsatile GH release through GHRH receptor binding, elevating IGF-1 and driving selective visceral fat reduction. It has additionally been studied off-label for metabolic health, NAFLD treatment, cognitive enhancement, and anti-aging body composition protocols.
Reading a comparison
A comparison places two records side by side; it does not merge them. Each description above is drawn from that compound's own record, and the two were not necessarily characterised by the same methods, at the same time, or to the same level of detail. Before comparing any attribute, it is worth establishing that both records describe the substance you think they describe — names are not identifiers, and two entries sharing a name can differ in salt form, stereochemistry or the convention used to state a mass. Where a figure carries no method beside it, the comparison is between two reported numbers rather than between two measurements.